Tofacitinib Citrate for the Treatment of Nail Dystrophy Associated With Alopecia Universalis
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چکیده
منابع مشابه
Remarkable Improvement of Nail Changes in Alopecia Areata Universalis with 10 Months of Treatment with Tofacitinib: A Case Report
Alopecia areata (AA) is a chronic, autoimmune disease. The main symptom is massive hair loss, localized or diffuse, in the scalp and the whole body. However, nails may also be involved, and brittleness, fragility and pitting can be signs of nail dystrophy in AA patients. Here, we report the case of a male patient with AA refractory to various treatments, including oral, topical and intralesiona...
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Alopecia areata is a common autoimmune disorder that targets hair follicles. Swarms of lymphocytes surround the basis of the follicles, inducing loss of pigmented terminal hair and subsequently inhibit further hair growth. Depending on the extent of involvement, alopecia areata can be associated with a dramatic reduction of quality of life. Currently, no targeted treatment option is available, ...
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Congenital alopecia universalis is one of the rarest anomaly which involves skin and appendages. The inheritance pattern can be autosomal recessive, X-linked recessive, or autosomal dominant. However, the most common is autosomal recessive form and it is the most severe phenotype. Twenty-nail dystrophy refers to the condition in which all the twenty nails are affected in the form of excessive r...
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AA: alopecia areata AU: alopecia universalis IL: interleukin SALT: Severity of Alopecia Tool INTRODUCTION Alopecia areata (AA) is an autoimmune disease distinguished by the appearance of nonscarring hair loss. Initially characterized by oval or round patches of hair loss, the disease can progress to multiple clinical presentations, including the alopecia universalis (AU) subtype in which there ...
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BACKGROUND Hirschsprung's disease is one of the commonest causes of intestinal obstruction in neonates because of gut motility disorder. It is characterized as a complex genetic heterogenous disorder with variable inheritance. Hirschsprung's disease occurs as an isolated phenotype in majority (70 %) of cases. In other cases it may be associated with syndromes (such as Down's syndrome, Waardenbu...
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ژورنال
عنوان ژورنال: JAMA Dermatology
سال: 2016
ISSN: 2168-6068
DOI: 10.1001/jamadermatol.2015.3772